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Intracellular hypoxia detection Hypoxyprobe-1 (Hypoxyprobe Inc, Burlington, USA) is a substituted 2-nitroimidazole compound known as pimonidazole
While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including mitochondria where its concentration in the matrix equals that of the cytosol
Diabetes UK
The generation of ROS leads to lipid peroxidation, mitochondrial dysfunction, and DNA fragmentation, which collectively contribute to cell death in the inner ear (Ramkumar et al
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